The Installer will check for X11 before installing.
You must have a version of X11 installed with a windows manager, e.g Apple's X11 for 10.4 to 10.5 or XQuartz for 10.6 to 10.11.
The Intel 2.6 version has programs that are Java based.
You will need to install the Java JDK (not just the JRE) to run these programs. Go to the Oracle and choose the newest version for Mac OS X.
There are two versions of the MacGDE suite: Universal (2.5) for 10.4 to 10.9 and Intel (2.6) for 10.7 to 10.11.
macgde_universal 2.5 80.1 Megabyte Zip archive which includes MacGDE source code
macgde_intel 2.6 95.1 Megabyte Zip archive which includes MacGDE source code
NOTE: macOS 10.9 and above has GateKepper to prevent unregistered applications from installing or running. MacGDE is not registered so to install it and start it the first time you will need to override this.
To override your security settings and open the app, i.e. Installer.command or MacGDE.app:
1. In the Finder, locate the "app" you want to open.
Don’t use Launchpad to do this. Launchpad doesn’t allow you to access the shortcut menu.
2. Press the Control key (right click), then click the "app" icon, then choose Open from the shortcut menu.
3. Click Open.
The "app" is saved as an exception to your security settings, and you can open it in the future by double-clicking it just as you can any registered app.
An additional download site is BioAfrica which also has GDELinux.
If you would like to set up an entire Bioinformatics resource running on the Unix system which incorporates GDE, then go to the BIRCH site developed by Dr. Brian Fristensky.